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Contraindicated. "Likely for major and/or lifestyle-threatening reactions for instance acute ergot toxicity characterised by peripheral vasospasm and ischemia in the extremities and also other tissues. "ergotamine will boost the level or effect of tazemetostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Stay clear of coadministration of olutasidenib (a CYP3A4 inducer) with sensitive CYP3A substrates Unless of course or else instructed in substrates prescribing details. If unavoidable, keep an eye on for lack of therapeutic influence of delicate CYP3A4 substrates.
caffeine decreases levels of levothyroxine by inhibition of GI absorption. Applies only to oral sort of both brokers. Use Caution/Keep an eye on. Caffeine (a sympathomimetic) concomitantly applied with oral levothyroxine may possibly increase the effects of sympathomimetics or thyroid hormone.
fosamprenavir will raise the level or result of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Contraindicated (1)itraconazole will increase the amount or outcome of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Keep track of Intently (one)ferric maltol, ergotamine. Possibly will increase amounts of the other by unspecified conversation system. Modify Therapy/Check Carefully. Coadministration of ferric maltol with sure oral remedies may possibly minimize the bioavailability of either ferric maltol and several oral prescription drugs.
artemether/lumefantrine will decrease the level or impact of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
acetazolamide will enhance the amount or influence of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.
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Keep track of Carefully (one)telotristat ethyl will lower the extent or result of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
ergotamine will raise the degree or influence of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
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dasatinib will raise the degree or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. website Contraindicated.